Title

Porphyrin Biphenyl and Isonipecotic Acid Hybrid Hosts and Their Recognition of Anion Guests

Author

Sandhya Pola

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Chemistry

Date of Award

Summer 2017

Abstract

The Starnes research group aims to develop porphyrin receptors for chiral and non-chiral guests through artificial host synthesis and the study of their host-guest binding properties. This thesis work focused on the synthesis of a variety of receptors and the study of their ability to bind to chiral and non-chiral guests. The project mainly focused on the development of a host for non-chiral guests—the shape selective recognition of anion guests. One host is characterized as a porphyrin-biphenyl hybrid. Two other hosts are characterized as porphyrin-isonipecotic acid hybrids; these three hosts have a pocket to bind guests that sit directly over the metal center. Guests are bound through hydrogen bonding and metal coordination interactions. Recognition studies of these hosts with a variety of non-chiral anions were conducted by ultraviolet/visible titrations, and binding constants, which are reported herein, were determined.

Advisor

Stephen D Starnes

Subject Categories

Chemistry | Physical Sciences and Mathematics

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